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  <title>Enzyme-Mediated and Transporter-Mediated Interactions of Antimicrobials</title>
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  <div class="pageHeader">
      
    <a href="/" id="sglogo" style="visibility:hidden"> <img class="sglogo" src="images/sgchars.png"/> </a>  
    <div id="xsTitle" class="tableTitle visible-xs visible-s" style="visibility:hidden">Mediated Interactions</div>
    <div id="normTitle" class="tableTitle hidden-xs hidden-s" style="visibility:hidden">Enzyme/Transporter Mediated Interactions</div>
    
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            <td class="colHeader enz-col-1 hidden-xs"><a href="#" data-toggle="modal" data-target="#tooltipModal" data-header="References" data-tooltip="Hansten PD, Horn JR. The Top 100 Drug Interactions: A Guide to Patient Management. Freeland (WA): H&amp;H Publications, 2015; primary literature; package inserts."><br/>Drug</a></td>
            <td class="colHeader enz-col-2 hidden-xs"><a href="#" data-toggle="modal" data-target="#rdModal" data-header="Enzyme/Transporter Mediated Interactions" data-type="Terminology" data-firstlabel="BCRP" data-first="breast cancer resistance protein" data-secondlabel="CYP450 nomenclature" data-second="e.g. 3A4: 3 = family, A = subfamily, 4 = gene" data-thirdlabel="OAT" data-third="organic anion transporter" data-fourthlabel="OATP" data-fourth="organic anion transporter polypeptide" data-fifthlabel="PGP" data-fifth="P-glycoprotein" data-sixthlabel="UGT" data-sixth="uridine diphosphate glucuronosyltransferase" data-footnotes="">Drug is <br>Substrate of</a></td>
            <td class="colHeader enz-col-3 hidden-xs"><a href="#" data-toggle="modal" data-target="#rdModal" data-header="Enzyme/Transporter Mediated Interactions" data-type="Terminology" data-firstlabel="BCRP" data-first="breast cancer resistance protein" data-secondlabel="CYP450 nomenclature" data-second="e.g. 3A4: 3 = family, A = subfamily, 4 = gene" data-thirdlabel="OAT" data-third="organic anion transporter" data-fourthlabel="OATP" data-fourth="organic anion transporter polypeptide" data-fifthlabel="OCT" data-fifth="organic cation transporter" data-sixthlabel="PGP" data-sixth="P-glycoprotein" data-seventhlabel="UGT" data-seventh="uridine diphosphate glucuronosyltransferase" data-footnotes="">Inhibited <br/>by Drug</a></td>
            <td class="colHeader enz-col-4 hidden-xs"><a href="#" data-toggle="modal" data-target="#rdModal" data-header="Enzyme/Transporter Mediated Interactions" data-type="Terminology" data-firstlabel="CYP450 nomenclature" data-first="e.g. 3A4: 3 = family, A = subfamily, 4 = gene" data-secondlabel="PGP" data-second="P-glycoprotein" data-footnotes="">Induced <br/>by Drug</a></td>
            <td class="colHeader enz-col-5 hidden-xs"><a href="#" data-toggle="modal" data-target="#tooltipModal" data-header="Impact on Serum Drug Concentrations" data-tooltip="Refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase, ↓=decrease, blank=no drugs should be affected">Impact on<br/>Serum Drug Conc</a></td>   
            
            <td class="colHeader enz-col-sm-1 visible-xs"> <a href="#" data-toggle="modal" data-target="#tooltipModal" data-header="References" data-tooltip="Hansten PD, Horn JR. The Top 100 Drug Interactions: A Guide to Patient Management. Freeland (WA): H&amp;H Publications, 2015; primary literature; package inserts."><br/>Drug </a></td>
            <td class="colHeader enz-col-sm-2 visible-xs"> Enzyme/Transporter<br/>Mediated Interactions</td>
          </tr>
        </thead>
      </table>
    </div>
    <div class="dataRows">
      <table class="mainTable" id="mainTable">
          
          <tr class="drugFamily">
            <td colspan="8"><b>Antibacterials</b></td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antibacterial-agents/macrolides/azithromycin">Azithromycin</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>Transporters: </b>PGP                                        
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>Transporters: </b>PGP (weak)                                         
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> mild ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antibacterial-agents/macrolides/azithromycin">Azithromycin</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Azithromycin" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="PGP (weak)"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="mild ↑"
                 data-footnotes="PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antibacterial-agents/chloramphenicol">Chloramphenicol</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               &nbsp;             </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>2C19, 3A4                                              
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antibacterial-agents/chloramphenicol">Chloramphenicol</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Chloramphenicol" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="2C19, 3A4"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antibacterial-agents/fluoroquinolones/ciprofloxacin">Ciprofloxacin</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               &nbsp;             </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>1A2; 3A4 (minor)                                              
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antibacterial-agents/fluoroquinolones/ciprofloxacin">Ciprofloxacin</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Ciprofloxacin" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="1A2; 3A4 (minor)"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antibacterial-agents/macrolides/clarithromycin">Clarithromycin</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP, OAT                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antibacterial-agents/macrolides/clarithromycin">Clarithromycin</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Clarithromycin" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="3A4"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="PGP, OAT"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|OAT: Organic Anion Transporter|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="">Clindamycin</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
              &nbsp;            
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> No effect expected </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="">Clindamycin</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Clindamycin" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="No effect expected"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antibacterial-agents/macrolides/erythromycin-base-esters">Erythromycin</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP 
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP, OAT                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antibacterial-agents/macrolides/erythromycin-base-esters">Erythromycin</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Erythromycin" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="3A4"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="PGP, OAT"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|OAT: Organic Anion Transporter|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antibacterial-agents/fluoroquinolones/levofloxacin">Levofloxacin</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               &nbsp;             </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>Transporters: </b>OCT                                         
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antibacterial-agents/fluoroquinolones/levofloxacin">Levofloxacin</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Levofloxacin" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="OCT"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="OCT: Organic Cation Transporter|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antibacterial-agents/nitroimidazoles/metronidazole">Metronidazole</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               &nbsp;             </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>2C9                                              
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antibacterial-agents/nitroimidazoles/metronidazole">Metronidazole</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Metronidazole" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="2C9"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antibacterial-agents/penicillins/antistaphylo-coccal-penicillins/nafcillin">Nafcillin</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               &nbsp;             </td>
            <td class="tblCell enz-col-3 hidden-xs">
              &nbsp;            
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               <b>CYP450: </b>2C9 (?), 3A4                                           
                  
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↓ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antibacterial-agents/penicillins/antistaphylo-coccal-penicillins/nafcillin">Nafcillin</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Nafcillin" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth="2C9 (?), 3A4"
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↓"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antibacterial-agents/fluoroquinolones/norfloxacin">Norfloxacin</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               &nbsp;             </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>1A2 (weak)                                              
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> mild ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antibacterial-agents/fluoroquinolones/norfloxacin">Norfloxacin</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Norfloxacin" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="1A2 (weak)"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="mild ↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antibacterial-agents/glyco-lipoglyco-peptides/oritavancin">Oritavancin</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               &nbsp;             </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>2C9 (weak), 2C19 (weak)                                              
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               <b>CYP450: </b>2D6 (weak), 3A4 (weak)                                           
                  
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> mild ↑ or ↓ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antibacterial-agents/glyco-lipoglyco-peptides/oritavancin">Oritavancin</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Oritavancin" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="2C9 (weak), 2C19 (weak)"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth="2D6 (weak), 3A4 (weak)"
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="mild ↑ or ↓"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antibacterial-agents/streptogramins/quinupristin-dalfopristin">Quinupristin-Dalfopristin</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               &nbsp;             </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>3A4                                              
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antibacterial-agents/streptogramins/quinupristin-dalfopristin">Quinupristin-Dalfopristin</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Quinupristin-Dalfopristin" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="3A4"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antimycobacterial-agents/rifampin">Rifampin</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>Transporters: </b>PGP                                        
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>Transporters: </b>OAT                                         
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               <b>CYP450: </b>1A2, 2B6, 2C8, 2C9, 2C19, 2D6 (weak), 3A4<br/><b>Transporters: </b>PGP                  
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↓ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antimycobacterial-agents/rifampin">Rifampin</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Rifampin" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="OAT"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth="1A2, 2B6, 2C8, 2C9, 2C19, 2D6 (weak), 3A4"
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth="PGP"
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↓"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|OAT: Organic Anion Transporter|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antibacterial-agents/rifamycin/rifaximin">Rifaximin</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP, OATP1A2, OATP1B1/3 
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>Transporters: </b>PGP                                         
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> No effect expected </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antibacterial-agents/rifamycin/rifaximin">Rifaximin</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Rifaximin" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP, OATP1A2, OATP1B1/3"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="PGP"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="No effect expected"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|OAT: Organic Anion Transporter|OATP: Organic Anion Transporter Polypeptide|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antibacterial-agents/ketolide/telithromycin">Telithromycin</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               &nbsp;             </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP (?)                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antibacterial-agents/ketolide/telithromycin">Telithromycin</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Telithromycin" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="3A4"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="PGP (?)"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/comparisons-1/adverse-effects/desensitization/tmp-smx-desensitization">TMP-SMX</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>SMX: 2C9 (major), 3A4                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>TMP: 2C8; SMX: 2C9                                              
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/comparisons-1/adverse-effects/desensitization/tmp-smx-desensitization">TMP-SMX</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="TMP-SMX" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="SMX: 2C9 (major), 3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="TMP: 2C8; SMX: 2C9"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antibacterial-agents/trimethoprim-sulfonamides/trimethoprim">Trimethoprim</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               &nbsp;             </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>2C8                                              
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antibacterial-agents/trimethoprim-sulfonamides/trimethoprim">Trimethoprim</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Trimethoprim" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="2C8"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          <tr class="drugFamily">
            <td colspan="8"><b>Antifungals</b></td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antifungal-agents/fluconazole">Fluconazole</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               &nbsp;             </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>2C9, 2C19, 3A4                                              
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antifungal-agents/fluconazole">Fluconazole</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Fluconazole" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="2C9, 2C19, 3A4"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antifungal-agents/isavuconazole?searchterm=Isavuconazole">Isavuconazole</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP, OCT2                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antifungal-agents/isavuconazole?searchterm=Isavuconazole">Isavuconazole</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Isavuconazole" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="3A4"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="PGP, OCT2"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|OCT: Organic Cation Transporter|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antifungal-agents/itraconazole">Itraconazole</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antifungal-agents/itraconazole">Itraconazole</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Itraconazole" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="3A4"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="PGP"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antifungal-agents/ketoconazole">Ketoconazole</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antifungal-agents/ketoconazole">Ketoconazole</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Ketoconazole" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="3A4"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="PGP"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antifungal-agents/posaconazole">Posaconazole</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>Transporters: </b>PGP                                        
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antifungal-agents/posaconazole">Posaconazole</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Posaconazole" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="3A4"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="PGP"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antifungal-agents/terbinafine">Terbinafine</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               &nbsp;             </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>2D6                                              
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antifungal-agents/terbinafine">Terbinafine</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Terbinafine" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="2D6"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antifungal-agents/voriconazole">Voriconazole</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>2C9, 2C19, 3A4                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>2C9, 2C19, 3A4                                              
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antifungal-agents/voriconazole">Voriconazole</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Voriconazole" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="2C9, 2C19, 3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="2C9, 2C19, 3A4"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          <tr class="drugFamily">
            <td colspan="8"><b>Antimycobacterials (Rifampin listed above)</b></td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antimycobacterial-agents/bedaquiline">Bedaquiline</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
              &nbsp;            
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> No effect expected </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antimycobacterial-agents/bedaquiline">Bedaquiline</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Bedaquiline" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="No effect expected"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="">Delamanid</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
              &nbsp;            
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> No effect expected </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="">Delamanid</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Delamanid" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="No effect expected"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antimycobacterial-agents/isoniazid">Isoniazid (INH)</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>2E1                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>2C19, 3A4                                              
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antimycobacterial-agents/isoniazid">Isoniazid (INH)</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Isoniazid (INH)" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="2E1"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="2C19, 3A4"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antimycobacterial-agents/rifabutin">Rifabutin</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
              &nbsp;            
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               <b>CYP450: </b>3A4                                           
                  
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↓ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antimycobacterial-agents/rifabutin">Rifabutin</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Rifabutin" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth="3A4"
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↓"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antimycobacterial-agents/rifapentine">Rifapentine</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               &nbsp;             </td>
            <td class="tblCell enz-col-3 hidden-xs">
              &nbsp;            
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               <b>CYP450: </b>2C9, 3A4                                           
                  
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↓ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antimycobacterial-agents/rifapentine">Rifapentine</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Rifapentine" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth="2C9, 3A4"
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↓"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antimycobacterial-agents/thalidomide">Thalidomide</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>2C19                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
              &nbsp;            
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> No effect expected </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antimycobacterial-agents/thalidomide">Thalidomide</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Thalidomide" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="2C19"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="No effect expected"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          <tr class="drugFamily">
            <td colspan="8"><b>Antiparasitics</b></td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiparasitic-agents/artemether-lumefantrine">Artemether-Lumefantrine</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4 (Art, Lum)                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>2D6 (Lum)                                              
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               <b>CYP450: </b>3A4 (Art)                                           
                  
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ or ↓ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiparasitic-agents/artemether-lumefantrine">Artemether-Lumefantrine</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Artemether-Lumefantrine" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4 (Art, Lum)"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="2D6 (Lum)"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth="3A4 (Art)"
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑ or ↓"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiparasitic-agents/chloroquine-phosphate">Chloroquine</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>2C8, 2D6                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>2D6                                              
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiparasitic-agents/chloroquine-phosphate">Chloroquine</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Chloroquine" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="2C8, 2D6"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="2D6"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiparasitic-agents/dapsone">Dapsone</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
              &nbsp;            
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> No effect expected </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiparasitic-agents/dapsone">Dapsone</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Dapsone" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="No effect expected"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiparasitic-agents/mefloquine">Mefloquine</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP 
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>Transporters: </b>PGP                                         
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiparasitic-agents/mefloquine">Mefloquine</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Mefloquine" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="PGP"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiparasitic-agents/praziquantel">Praziquantel</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
              &nbsp;            
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> No effect expected </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiparasitic-agents/praziquantel">Praziquantel</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Praziquantel" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="No effect expected"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiparasitic-agents/primaquine-phosphate">Primaquine</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>2D6, others?                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
              &nbsp;            
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> No effect expected </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiparasitic-agents/primaquine-phosphate">Primaquine</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Primaquine" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="2D6, others?"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="No effect expected"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiparasitic-agents/atovaquone-proguanil">Proguanil</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>2C19 (→cycloguanil)                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
              &nbsp;            
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> No effect expected </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiparasitic-agents/atovaquone-proguanil">Proguanil</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Proguanil" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="2C19 (→cycloguanil)"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="No effect expected"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiparasitic-agents/quinine-sulfate">Quinine sulfate</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>main 3A4, also 1A2, 2C9, 2D6                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>2D6                                              
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiparasitic-agents/quinine-sulfate">Quinine sulfate</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Quinine sulfate" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="main 3A4, also 1A2, 2C9, 2D6"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="2D6"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antibacterial-agents/nitroimidazoles/tinidazole">Tinidazole</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
              &nbsp;            
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> No effect expected </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antibacterial-agents/nitroimidazoles/tinidazole">Tinidazole</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Tinidazole" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="No effect expected"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          <tr class="drugFamily">
            <td colspan="8"><b>Antivirals (hepatitis C)</b></td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiviral-agents/daclatasvir">Daclatasvir</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP 
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
              &nbsp;            
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> No effect expected </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiviral-agents/daclatasvir">Daclatasvir</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Daclatasvir" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="No effect expected"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiviral-agents/paritaprevir-ritonavir-ombitasvir-dasabuvir">Dasabuvir</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP, OATP1B1 
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>2C8<br/><b>Transporters: </b>UGT1A1, OATP1B1, OATP1B3                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiviral-agents/paritaprevir-ritonavir-ombitasvir-dasabuvir">Dasabuvir</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Dasabuvir" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP, OATP1B1"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="2C8"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="UGT1A1, OATP1B1, OATP1B3"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|OAT: Organic Anion Transporter|OATP: Organic Anion Transporter Polypeptide|PGP: P-glycoprotein|UGT: Uridine Diphosphate Glucuronosyltransferase|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiviral-agents/zepatier-elbasvir-grazoprevir">Elbasvir</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP 
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>Transporters: </b>BCRP                                         
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiviral-agents/zepatier-elbasvir-grazoprevir">Elbasvir</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Elbasvir" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="BCRP"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="BCRP: Breast Cancer Resistance Protein|CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="">Glecaprevir</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>Transporters: </b>PGP, BCRP, OATP1B1/3                                        
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>1A2 (weak), 3A4 (weak)<br/><b>Transporters: </b>PGP, BCRP, OATP1B1/3, UGT1A1 (weak)                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="">Glecaprevir</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Glecaprevir" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP, BCRP, OATP1B1/3"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="1A2 (weak), 3A4 (weak)"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="PGP, BCRP, OATP1B1/3, UGT1A1 (weak)"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="BCRP: Breast Cancer Resistance Protein|CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|OAT: Organic Anion Transporter|OATP: Organic Anion Transporter Polypeptide|PGP: P-glycoprotein|UGT: Uridine Diphosphate Glucuronosyltransferase|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiviral-agents/zepatier-elbasvir-grazoprevir">Grazoprevir</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP, OATP1B1/3 
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>3A4 (weak)<br/><b>Transporters: </b>BCRP                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiviral-agents/zepatier-elbasvir-grazoprevir">Grazoprevir</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Grazoprevir" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP, OATP1B1/3"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="3A4 (weak)"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="BCRP"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="BCRP: Breast Cancer Resistance Protein|CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|OAT: Organic Anion Transporter|OATP: Organic Anion Transporter Polypeptide|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiviral-agents/ledipasivir-sofosbuvir-harvoni">Ledipasvir</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>Transporters: </b>PGP, BCRP                                        
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>Transporters: </b>PGP, BCRP                                         
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiviral-agents/ledipasivir-sofosbuvir-harvoni">Ledipasvir</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Ledipasvir" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP, BCRP"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="PGP, BCRP"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="BCRP: Breast Cancer Resistance Protein|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiviral-agents/paritaprevir-ritonavir-ombitasvir-dasabuvir">Ombitasvir</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP 
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>Transporters: </b>2C8, UGT1A1                                         
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiviral-agents/paritaprevir-ritonavir-ombitasvir-dasabuvir">Ombitasvir</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Ombitasvir" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="2C8, UGT1A1"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|PGP: P-glycoprotein|UGT: Uridine Diphosphate Glucuronosyltransferase|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiviral-agents/paritaprevir-ritonavir-ombitasvir-dasabuvir">Paritaprevir</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>2C8, 2D6, 3A4<br/><b>Transporters: </b>PGP 
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>Transporters: </b>UGT1A1, OATP1B1                                         
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiviral-agents/paritaprevir-ritonavir-ombitasvir-dasabuvir">Paritaprevir</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Paritaprevir" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="2C8, 2D6, 3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="UGT1A1, OATP1B1"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|OAT: Organic Anion Transporter|OATP: Organic Anion Transporter Polypeptide|PGP: P-glycoprotein|UGT: Uridine Diphosphate Glucuronosyltransferase|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="">Pibrentasvir</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>Transporters: </b>PGP, BCRP                                        
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>1A2 (weak), 3A4 (weak)<br/><b>Transporters: </b>PGP, BCRP, OATP1B1/3, UGT1A1 (weak)                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="">Pibrentasvir</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Pibrentasvir" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP, BCRP"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="1A2 (weak), 3A4 (weak)"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="PGP, BCRP, OATP1B1/3, UGT1A1 (weak)"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="BCRP: Breast Cancer Resistance Protein|CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|OAT: Organic Anion Transporter|OATP: Organic Anion Transporter Polypeptide|PGP: P-glycoprotein|UGT: Uridine Diphosphate Glucuronosyltransferase|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiviral-agents/simeprevir">Simeprevir</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP, OATP1B1/3 
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>1A2 (weak), 3A4 (gut only)<br/><b>Transporters: </b>PGP, OATP1B1/3                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiviral-agents/simeprevir">Simeprevir</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Simeprevir" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP, OATP1B1/3"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="1A2 (weak), 3A4 (gut only)"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="PGP, OATP1B1/3"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|OAT: Organic Anion Transporter|OATP: Organic Anion Transporter Polypeptide|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiviral-agents/sofosbuvir">Sofosbuvir</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>Transporters: </b>PGP, BCRP                                        
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
              &nbsp;            
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> No effect expected </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiviral-agents/sofosbuvir">Sofosbuvir</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Sofosbuvir" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP, BCRP"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="No effect expected"
                 data-footnotes="BCRP: Breast Cancer Resistance Protein|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiviral-agents/epclusa-sofosbuvir-velpatasvir">Velpatasvir</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>2B6, 2C8, 3A4<br/><b>Transporters: </b>PGP, BCRP, OATP1B1/3 
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>Transporters: </b>PGP, BCRP, OATP1B1/3, OATP2B1                                         
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiviral-agents/epclusa-sofosbuvir-velpatasvir">Velpatasvir</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Velpatasvir" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="2B6, 2C8, 3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP, BCRP, OATP1B1/3"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="PGP, BCRP, OATP1B1/3, OATP2B1"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="BCRP: Breast Cancer Resistance Protein|CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|OAT: Organic Anion Transporter|OATP: Organic Anion Transporter Polypeptide|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          <tr class="drugFamily">
            <td colspan="8"><b>Antivirals (herpesvirus)</b></td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiviral-agents/cidofovir">Cidofovir</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>Transporters: </b>OAT1, OAT3                                        
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
              &nbsp;            
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> No effect expected </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiviral-agents/cidofovir">Cidofovir</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Cidofovir" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="OAT1, OAT3"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="No effect expected"
                 data-footnotes="OAT: Organic Anion Transporter|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          <tr class="drugFamily">
            <td colspan="8"><b>Antiretrovirals</b></td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiretroviral-agents/atazanavir">Atazanavir (ATV)</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP 
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>1A2, 2C8, 3A4<br/><b>Transporters: </b>UGT1A1                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiretroviral-agents/atazanavir">Atazanavir (ATV)</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Atazanavir (ATV)" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="1A2, 2C8, 3A4"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="UGT1A1"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|PGP: P-glycoprotein|UGT: Uridine Diphosphate Glucuronosyltransferase|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiretroviral-agents/cobicistat">Cobicistat</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>2D6, 3A4                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>2D6, 3A4<br/><b>Transporters: </b>PGP, BCRP, OATP1B1, OATP1B3                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiretroviral-agents/cobicistat">Cobicistat</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Cobicistat" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="2D6, 3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="2D6, 3A4"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="PGP, BCRP, OATP1B1, OATP1B3"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="BCRP: Breast Cancer Resistance Protein|CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|OAT: Organic Anion Transporter|OATP: Organic Anion Transporter Polypeptide|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiretroviral-agents/darunavir">Darunavir (DRV)</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>3A4                                              
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiretroviral-agents/darunavir">Darunavir (DRV)</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Darunavir (DRV)" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="3A4"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiretroviral-agents/delavirdine">Delavirdine (DLV)</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>2D6, 3A4                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>2C9, 2C19, 3A4                                              
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiretroviral-agents/delavirdine">Delavirdine (DLV)</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Delavirdine (DLV)" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="2D6, 3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="2C9, 2C19, 3A4"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiretroviral-agents/dolutegravir">Dolutegravir (DTG)</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>UGT1A1 
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
              &nbsp;            
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> No effect expected </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiretroviral-agents/dolutegravir">Dolutegravir (DTG)</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Dolutegravir (DTG)" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="UGT1A1"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="No effect expected"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|UGT: Uridine Diphosphate Glucuronosyltransferase|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiretroviral-agents/efavirenz">Efavirenz (EFV)</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>2B6, 3A4                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>2B6, 2C9, 2C19                                              
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               <b>CYP450: </b>2C19, 3A4                                           
                  
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ or ↓ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiretroviral-agents/efavirenz">Efavirenz (EFV)</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Efavirenz (EFV)" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="2B6, 3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="2B6, 2C9, 2C19"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth="2C19, 3A4"
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑ or ↓"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiretroviral-agents/elvitegravir">Elvitegravir (EVG)</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>CYP3A4<br/><b>Transporters: </b>UGT1A1/3 
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>Transporters: </b>PGP (weak)                                         
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               <b>CYP450: </b>2C9 (weak)                                           
                  
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> mild ↑ or ↓ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiretroviral-agents/elvitegravir">Elvitegravir (EVG)</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Elvitegravir (EVG)" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="CYP3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="UGT1A1/3"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="PGP (weak)"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth="2C9 (weak)"
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="mild ↑ or ↓"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|PGP: P-glycoprotein|UGT: Uridine Diphosphate Glucuronosyltransferase|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiretroviral-agents/etravirine">Etravirine (ETR)</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>2C9, 2C19, 3A4                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>2C9; 2C19 (weak)                                              
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               <b>CYP450: </b>3A4                                           
                  
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ or ↓ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiretroviral-agents/etravirine">Etravirine (ETR)</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Etravirine (ETR)" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="2C9, 2C19, 3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="2C9; 2C19 (weak)"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth="3A4"
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑ or ↓"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiretroviral-agents/fosamprenavir">Fosamprenavir (FPV)</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>3A4                                              
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiretroviral-agents/fosamprenavir">Fosamprenavir (FPV)</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Fosamprenavir (FPV)" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="3A4"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiretroviral-agents/indinavir">Indinavir (IDV)</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP 
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiretroviral-agents/indinavir">Indinavir (IDV)</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Indinavir (IDV)" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="3A4"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="PGP"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiretroviral-agents/kaletra">Lopinavir (LPV)</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
              &nbsp;            
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiretroviral-agents/kaletra">Lopinavir (LPV)</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Lopinavir (LPV)" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiretroviral-agents/maraviroc">Maraviroc (MVC)</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP 
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>2D6                                              
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiretroviral-agents/maraviroc">Maraviroc (MVC)</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Maraviroc (MVC)" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="2D6"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiretroviral-agents/nelfinavir">Nelfinavir (NFV)</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>2C19, 3A4<br/><b>Transporters: </b>PGP 
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               <b>CYP450: </b>3A4 (?)                                           
                  
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ or ↓ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiretroviral-agents/nelfinavir">Nelfinavir (NFV)</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Nelfinavir (NFV)" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="2C19, 3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="3A4"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="PGP"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth="3A4 (?)"
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑ or ↓"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiretroviral-agents/nevirapine">Nevirapine (NVP)</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>2B6, 3A4                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
              &nbsp;            
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               <b>CYP450: </b>3A4                                           
                  
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↓ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiretroviral-agents/nevirapine">Nevirapine (NVP)</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Nevirapine (NVP)" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="2B6, 3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth="3A4"
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↓"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiretroviral-agents/raltegravir">Raltegravir (RAL)</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>Transporters: </b>UGT                                        
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
              &nbsp;            
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> No effect expected </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiretroviral-agents/raltegravir">Raltegravir (RAL)</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Raltegravir (RAL)" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="UGT"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="No effect expected"
                 data-footnotes="UGT: Uridine Diphosphate Glucuronosyltransferase|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiretroviral-agents/rilpivirine">Rilpivirine (RPV)</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
              &nbsp;            
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> No effect expected </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiretroviral-agents/rilpivirine">Rilpivirine (RPV)</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Rilpivirine (RPV)" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="No effect expected"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiretroviral-agents/ritonavir">Ritonavir (RTV)</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP 
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>2D6, 3A4<br/><b>Transporters: </b>PGP                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               <b>CYP450: </b>1A2, 2B6, 2C9, 2C19, 3A4 (long term)<br/><b>Transporters: </b>PGP (long term), UGT                  
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ or ↓ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiretroviral-agents/ritonavir">Ritonavir (RTV)</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Ritonavir (RTV)" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="2D6, 3A4"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="PGP"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth="1A2, 2B6, 2C9, 2C19, 3A4 (long term)"
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth="PGP (long term), UGT"
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑ or ↓"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|PGP: P-glycoprotein|UGT: Uridine Diphosphate Glucuronosyltransferase|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiretroviral-agents/saquinavir">Saquinavir (SQV)</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP 
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiretroviral-agents/saquinavir">Saquinavir (SQV)</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Saquinavir (SQV)" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="3A4"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="PGP"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
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            </td>
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          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiretroviral-agents/tenofovir-alafenamide-fumarate-taf">Tenofovir alaf fum (TAF)</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>Transporters: </b>PGP, BCRP, OATP1B1/3                                        
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
              &nbsp;            
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> No effect expected </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiretroviral-agents/tenofovir-alafenamide-fumarate-taf">Tenofovir alaf fum (TAF)</a></td>
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              <a id="tableLink" 
                 href="#" 
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                 data-target="#rdModal" 
                 data-header="Tenofovir alaf fum (TAF)" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP, BCRP, OATP1B1/3"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="No effect expected"
                 data-footnotes="BCRP: Breast Cancer Resistance Protein|CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|OAT: Organic Anion Transporter|OATP: Organic Anion Transporter Polypeptide|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
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          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiretroviral-agents/tipranavir">Tipranavir (TPV)</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP 
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>Transporters: </b>OAT                                         
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               <b>Transporters: </b>PGP (weak)                                       
                  
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ or ↓ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/sanford-guide-online/drug-information/antiretroviral-agents/tipranavir">Tipranavir (TPV)</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Tipranavir (TPV)" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="OAT"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth="PGP (weak)"
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑ or ↓"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|OAT: Organic Anion Transporter|OATP: Organic Anion Transporter Polypeptide|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
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            </td>
          </tr>
        
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