text/html enzyme-table.html — 172 KB

File contents

<!DOCTYPE html>
<html>
<head>
  <meta http-equiv="Content-Type" content="text/html; charset=utf-8">
  <meta name="viewport" content="width=device-width, initial-scale=1 user-scalable=yes">
  <base target="_top">
  <link rel="stylesheet" type="text/css" href="styles/bootstrap-3.3.5.css">
  <link rel="stylesheet" type="text/css" href="styles/dosingtables2.css">
  <script type="text/javascript" src="scripts/jquery-2.1.4.min.js"></script>
  <script type="text/javascript" src="scripts/bootstrap-3.3.5.min.js"></script>
  <script> 
    window.onload = function() { 
      try{
        if(window.self !== window.top){
          document.getElementById("xsTitle").className = "hidden";
          document.getElementById("normTitle").className = "hidden";
          document.getElementById("sglogo").className = "hidden";
          document.getElementById("search").placeholder = "Search this table"
        }else{
          document.getElementById("xsTitle").style.visibility = "visible";
          document.getElementById("normTitle").style.visibility = "visible";
          document.getElementById("sglogo").style.visibility = "visible";
          document.getElementById("search").placeholder = "Search Mediated Interactions"
        }
      } catch (e) { } 
    }; 
  </script>
  <title>Enzyme-Mediated and Transporter-Mediated Interactions of Antimicrobials</title>
</head>
<body>



  <div class="pageHeader">
      
    <a href="/" id="sglogo" style="visibility:hidden"> <img class="sglogo" src="images/sgchars.png"/> </a>  
    <div id="xsTitle" class="tableTitle visible-xs visible-s" style="visibility:hidden">Mediated Interactions</div>
    <div id="normTitle" class="tableTitle hidden-xs hidden-s" style="visibility:hidden">Enzyme/Transporter Mediated Interactions</div>
    
    <input type="text" class="search searchBox hidden-xs" id="search" placeholder="Search" />
    <span class="glyphicon glyphicon-search searchIcon hidden-xs" aria-hidden="true"></span>
    <button type="button" class="btn btn-default visible-xs searchIcon" data-toggle="modal" data-target="#searchModal"> 
      <span class="glyphicon glyphicon-search searchIconSm"  />
    </button>
    <hr class="headerHr">
  </div>
  
  <div class="dataTable">
    <div class="fixedHeaders">
      <table class="mainTableHeaders">
        <thead>
          <tr>
            <td class="colHeader enz-col-1 hidden-xs"><a href="#" data-toggle="modal" data-target="#tooltipModal" data-header="References" data-tooltip="Hansten PD, Horn JR. The Top 100 Drug Interactions: A Guide to Patient Management. Freeland (WA): H&amp;H Publications, 2015; primary literature; package inserts."><br/>Drug</a></td>
            <td class="colHeader enz-col-2 hidden-xs"><a href="#" data-toggle="modal" data-target="#rdModal" data-header="Enzyme/Transporter Mediated Interactions" data-type="Terminology" data-firstlabel="BCRP" data-first="breast cancer resistance protein" data-secondlabel="CYP450 nomenclature" data-second="e.g. 3A4: 3 = family, A = subfamily, 4 = gene" data-thirdlabel="OAT" data-third="organic anion transporter" data-fourthlabel="OATP" data-fourth="organic anion transporter polypeptide" data-fifthlabel="PGP" data-fifth="P-glycoprotein" data-sixthlabel="UGT" data-sixth="uridine diphosphate glucuronosyltransferase" data-footnotes="">Drug is <br>Substrate of</a></td>
            <td class="colHeader enz-col-3 hidden-xs"><a href="#" data-toggle="modal" data-target="#rdModal" data-header="Enzyme/Transporter Mediated Interactions" data-type="Terminology" data-firstlabel="BCRP" data-first="breast cancer resistance protein" data-secondlabel="CYP450 nomenclature" data-second="e.g. 3A4: 3 = family, A = subfamily, 4 = gene" data-thirdlabel="OAT" data-third="organic anion transporter" data-fourthlabel="OATP" data-fourth="organic anion transporter polypeptide" data-fifthlabel="OCT" data-fifth="organic cation transporter" data-sixthlabel="PGP" data-sixth="P-glycoprotein" data-seventhlabel="UGT" data-seventh="uridine diphosphate glucuronosyltransferase" data-footnotes="">Inhibited <br/>by Drug</a></td>
            <td class="colHeader enz-col-4 hidden-xs"><a href="#" data-toggle="modal" data-target="#rdModal" data-header="Enzyme/Transporter Mediated Interactions" data-type="Terminology" data-firstlabel="CYP450 nomenclature" data-first="e.g. 3A4: 3 = family, A = subfamily, 4 = gene" data-secondlabel="PGP" data-second="P-glycoprotein" data-footnotes="">Induced <br/>by Drug</a></td>
            <td class="colHeader enz-col-5 hidden-xs"><a href="#" data-toggle="modal" data-target="#tooltipModal" data-header="Impact on Serum Drug Concentrations" data-tooltip="Refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase, ↓=decrease, blank=no drugs should be affected">Impact on<br/>Serum Drug Conc</a></td>   
            
            <td class="colHeader enz-col-sm-1 visible-xs"> <a href="#" data-toggle="modal" data-target="#tooltipModal" data-header="References" data-tooltip="Hansten PD, Horn JR. The Top 100 Drug Interactions: A Guide to Patient Management. Freeland (WA): H&amp;H Publications, 2015; primary literature; package inserts."><br/>Drug </a></td>
            <td class="colHeader enz-col-sm-2 visible-xs"> Enzyme/Transporter<br/>Mediated Interactions</td>
          </tr>
        </thead>
      </table>
    </div>
    <div class="dataRows">
      <table class="mainTable" id="mainTable">
          
          <tr class="drugFamily">
            <td colspan="8"><b>Antibacterials</b></td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/edbf8485be234f429f1c6677aa82c3f6">Azithromycin</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>Transporters: </b>PGP                                        
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>Transporters: </b>PGP (weak)                                         
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> mild ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/edbf8485be234f429f1c6677aa82c3f6">Azithromycin</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Azithromycin" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="PGP (weak)"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="mild ↑"
                 data-footnotes="PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/47f9d8a0d79b4ab0bc48bc14870f5f09">Chloramphenicol</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               &nbsp;             </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>2C19, 3A4                                              
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/47f9d8a0d79b4ab0bc48bc14870f5f09">Chloramphenicol</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Chloramphenicol" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="2C19, 3A4"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/204deaab57394233a3926b6fe77b8f9d">Ciprofloxacin</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               &nbsp;             </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>1A2; 3A4 (minor)                                              
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/204deaab57394233a3926b6fe77b8f9d">Ciprofloxacin</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Ciprofloxacin" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="1A2; 3A4 (minor)"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/24829670c7dd402090a36841968d4a0a">Clarithromycin</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP, OAT                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/24829670c7dd402090a36841968d4a0a">Clarithromycin</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Clarithromycin" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="3A4"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="PGP, OAT"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|OAT: Organic Anion Transporter|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="">Clindamycin</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
              &nbsp;            
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> No effect expected </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="">Clindamycin</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Clindamycin" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="No effect expected"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/b758035793d94dcea21ecb87f0d33919">Erythromycin</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP 
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP, OAT                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/b758035793d94dcea21ecb87f0d33919">Erythromycin</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Erythromycin" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="3A4"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="PGP, OAT"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|OAT: Organic Anion Transporter|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/489123e0a52c4d91bd575ae0351e1bd1">Levofloxacin</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               &nbsp;             </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>Transporters: </b>OCT                                         
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/489123e0a52c4d91bd575ae0351e1bd1">Levofloxacin</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Levofloxacin" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="OCT"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="OCT: Organic Cation Transporter|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="">Meropenem</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>Transporters: </b>OAT1, OAT3                                        
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
              &nbsp;            
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs">  </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="">Meropenem</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Meropenem" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="OAT1, OAT3"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh=""
                 data-footnotes="OAT: Organic Anion Transporter">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/5165de0dbf6940a68524c9c7218a5707">Metronidazole</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               &nbsp;             </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>2C9                                              
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/5165de0dbf6940a68524c9c7218a5707">Metronidazole</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Metronidazole" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="2C9"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/b74be73b3cc04e9ca37589016dc3fade">Nafcillin</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               &nbsp;             </td>
            <td class="tblCell enz-col-3 hidden-xs">
              &nbsp;            
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               <b>CYP450: </b>2C9 (?), 3A4                                           
                  
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↓ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/b74be73b3cc04e9ca37589016dc3fade">Nafcillin</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Nafcillin" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth="2C9 (?), 3A4"
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↓"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/ed0268d2f9384f9aa47f9e41556d4860">Norfloxacin</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               &nbsp;             </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>1A2 (weak)                                              
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> mild ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/ed0268d2f9384f9aa47f9e41556d4860">Norfloxacin</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Norfloxacin" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="1A2 (weak)"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="mild ↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/0e2d1daee464429db7f54a8f7e42fa6c">Oritavancin</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               &nbsp;             </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>2C9 (weak), 2C19 (weak)                                              
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               <b>CYP450: </b>2D6 (weak), 3A4 (weak)                                           
                  
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> mild ↑ or ↓ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/0e2d1daee464429db7f54a8f7e42fa6c">Oritavancin</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Oritavancin" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="2C9 (weak), 2C19 (weak)"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth="2D6 (weak), 3A4 (weak)"
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="mild ↑ or ↓"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/a88cd0ea13be4b3d8e40e46367c195da">Quinupristin-Dalfopristin</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               &nbsp;             </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>3A4                                              
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/a88cd0ea13be4b3d8e40e46367c195da">Quinupristin-Dalfopristin</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Quinupristin-Dalfopristin" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="3A4"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/c4994fee9869f9591421e67ef1d72321">Rifampin</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>Transporters: </b>PGP                                        
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>Transporters: </b>OAT                                         
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               <b>CYP450: </b>1A2, 2B6, 2C8, 2C9, 2C19, 2D6 (weak), 3A4<br/><b>Transporters: </b>PGP                  
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↓ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/c4994fee9869f9591421e67ef1d72321">Rifampin</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Rifampin" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="OAT"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth="1A2, 2B6, 2C8, 2C9, 2C19, 2D6 (weak), 3A4"
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth="PGP"
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↓"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|OAT: Organic Anion Transporter|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/fcac0af8b8b4491f8e119c7b5ce70124">Rifaximin</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP, OATP1A2, OATP1B1/3 
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>Transporters: </b>PGP                                         
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> No effect expected </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/fcac0af8b8b4491f8e119c7b5ce70124">Rifaximin</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Rifaximin" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP, OATP1A2, OATP1B1/3"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="PGP"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="No effect expected"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|OAT: Organic Anion Transporter|OATP: Organic Anion Transporter Polypeptide|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/9dcd621662a6448587654f03a8a432bf">Telithromycin</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               &nbsp;             </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP (?)                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/9dcd621662a6448587654f03a8a432bf">Telithromycin</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Telithromycin" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="3A4"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="PGP (?)"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="">Tigecycline</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>Transporters: </b>PGP                                        
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
              &nbsp;            
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs">  </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="">Tigecycline</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Tigecycline" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh=""
                 data-footnotes="PGP: P-glycoprotein">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/d388829c7661d0d74ad888331eee4c0d">TMP-SMX</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>SMX: 2C9 (major), 3A4                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>TMP: 2C8; SMX: 2C9                                              
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/d388829c7661d0d74ad888331eee4c0d">TMP-SMX</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="TMP-SMX" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="SMX: 2C9 (major), 3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="TMP: 2C8; SMX: 2C9"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/c4251de4e70c4b0ea485166dd4b418ca">Trimethoprim</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               &nbsp;             </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>2C8                                              
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/c4251de4e70c4b0ea485166dd4b418ca">Trimethoprim</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Trimethoprim" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="2C8"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          <tr class="drugFamily">
            <td colspan="8"><b>Antifungals</b></td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/3aee13e0dce72035c4adfc5f82e3c3b7">Fluconazole</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               &nbsp;             </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>2C9, 2C19, 3A4                                              
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/3aee13e0dce72035c4adfc5f82e3c3b7">Fluconazole</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Fluconazole" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="2C9, 2C19, 3A4"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/3cf4a42c95184f48a1d500339adddd2d">Isavuconazole</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP, OCT2                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/3cf4a42c95184f48a1d500339adddd2d">Isavuconazole</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Isavuconazole" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="3A4"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="PGP, OCT2"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|OCT: Organic Cation Transporter|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/c6c45a491c2fbe6f2307f528bc25e58c">Itraconazole</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/c6c45a491c2fbe6f2307f528bc25e58c">Itraconazole</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Itraconazole" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="3A4"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="PGP"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/39d8e0de2569961f21bca555134dc939">Ketoconazole</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/39d8e0de2569961f21bca555134dc939">Ketoconazole</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Ketoconazole" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="3A4"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="PGP"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/66b15ef6d5fcc904815ddbfefada43bb">Posaconazole</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>Transporters: </b>PGP                                        
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/66b15ef6d5fcc904815ddbfefada43bb">Posaconazole</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Posaconazole" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="3A4"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="PGP"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/f3b2a58a1f9acf35b8f1cd200d396683">Terbinafine</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               &nbsp;             </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>2D6                                              
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/f3b2a58a1f9acf35b8f1cd200d396683">Terbinafine</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Terbinafine" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="2D6"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/4f4303b536c9803ee5c03585605c177d">Voriconazole</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>2C9, 2C19, 3A4                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>2C9, 2C19, 3A4                                              
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/4f4303b536c9803ee5c03585605c177d">Voriconazole</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Voriconazole" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="2C9, 2C19, 3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="2C9, 2C19, 3A4"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          <tr class="drugFamily">
            <td colspan="8"><b>Antimycobacterials (Rifampin listed above)</b></td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/7142c1e0-1e50-4cec-8293-c5107301158a">Bedaquiline</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
              &nbsp;            
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> No effect expected </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/7142c1e0-1e50-4cec-8293-c5107301158a">Bedaquiline</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Bedaquiline" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="No effect expected"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="">Delamanid</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
              &nbsp;            
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> No effect expected </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="">Delamanid</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Delamanid" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="No effect expected"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/3963668f9b174bb155c3fc06fbdf5734">Isoniazid (INH)</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>2E1                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>2C19, 3A4                                              
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/3963668f9b174bb155c3fc06fbdf5734">Isoniazid (INH)</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Isoniazid (INH)" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="2E1"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="2C19, 3A4"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/f9557d57a6c766815a2a3042254efdde">Rifabutin</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
              &nbsp;            
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               <b>CYP450: </b>3A4                                           
                  
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↓ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/f9557d57a6c766815a2a3042254efdde">Rifabutin</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Rifabutin" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth="3A4"
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↓"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/3288c2ee4d2c7c18de1c97f1791b014e">Rifapentine</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               &nbsp;             </td>
            <td class="tblCell enz-col-3 hidden-xs">
              &nbsp;            
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               <b>CYP450: </b>2C9, 3A4                                           
                  
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↓ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/3288c2ee4d2c7c18de1c97f1791b014e">Rifapentine</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Rifapentine" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth="2C9, 3A4"
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↓"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/879a6b7e090fc97b4027745831702c05">Thalidomide</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>2C19                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
              &nbsp;            
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> No effect expected </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/879a6b7e090fc97b4027745831702c05">Thalidomide</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Thalidomide" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="2C19"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="No effect expected"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          <tr class="drugFamily">
            <td colspan="8"><b>Antiparasitics</b></td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/cb23ae8c1d2fc2fc34859f07ef76202f">Artemether-Lumefantrine</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4 (Art, Lum)                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>2D6 (Lum)                                              
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               <b>CYP450: </b>3A4 (Art)                                           
                  
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ or ↓ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/cb23ae8c1d2fc2fc34859f07ef76202f">Artemether-Lumefantrine</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Artemether-Lumefantrine" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4 (Art, Lum)"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="2D6 (Lum)"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth="3A4 (Art)"
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑ or ↓"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/25df93ea664190f4c77709548bf33b5f">Chloroquine</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>2C8, 2D6                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>2D6                                              
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/25df93ea664190f4c77709548bf33b5f">Chloroquine</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Chloroquine" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="2C8, 2D6"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="2D6"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/ae7312eb6e45c9541416ec1597fa44bb">Dapsone</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
              &nbsp;            
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> No effect expected </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/ae7312eb6e45c9541416ec1597fa44bb">Dapsone</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Dapsone" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="No effect expected"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/789879eb774fe993e5b9544b88d3c11a">Mefloquine</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP 
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>Transporters: </b>PGP                                         
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/789879eb774fe993e5b9544b88d3c11a">Mefloquine</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Mefloquine" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="PGP"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/63555fede2fcb0a817ec342b2d964c7d">Praziquantel</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
              &nbsp;            
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> No effect expected </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/63555fede2fcb0a817ec342b2d964c7d">Praziquantel</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Praziquantel" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="No effect expected"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/f6ac0ce6a5d24399068b1c8fc77d807c">Primaquine</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>2D6, others?                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
              &nbsp;            
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> No effect expected </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/f6ac0ce6a5d24399068b1c8fc77d807c">Primaquine</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Primaquine" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="2D6, others?"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="No effect expected"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/a3671bb5e379049f196121a05e3e864d">Proguanil</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>2C19 (→cycloguanil)                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
              &nbsp;            
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> No effect expected </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/a3671bb5e379049f196121a05e3e864d">Proguanil</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Proguanil" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="2C19 (→cycloguanil)"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="No effect expected"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/3a1b47a2f842647655196c88aa68a388">Quinine sulfate</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>main 3A4, also 1A2, 2C9, 2D6                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>2D6                                              
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/3a1b47a2f842647655196c88aa68a388">Quinine sulfate</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Quinine sulfate" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="main 3A4, also 1A2, 2C9, 2D6"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="2D6"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/ccacb132cf4d4e6f8f249cfac5a2e246">Tinidazole</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
              &nbsp;            
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> No effect expected </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/ccacb132cf4d4e6f8f249cfac5a2e246">Tinidazole</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Tinidazole" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="No effect expected"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          <tr class="drugFamily">
            <td colspan="8"><b>Antivirals (hepatitis C)</b></td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/245c0fda039b4e9188f1cf351a2351c1">Daclatasvir</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP 
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>Transporters: </b>PGP, OATP1B1/3,  BCRP                                         
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/245c0fda039b4e9188f1cf351a2351c1">Daclatasvir</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Daclatasvir" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="PGP, OATP1B1/3,  BCRP"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="BCRP: Breast Cancer Resistance Protein|CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|OAT: Organic Anion Transporter|OATP: Organic Anion Transporter Polypeptide|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/549f3c04-4b0c-433a-ab6d-7a65b7679240">Dasabuvir</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP, OATP1B1 
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>2C8<br/><b>Transporters: </b>UGT1A1, OATP1B1, OATP1B3                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/549f3c04-4b0c-433a-ab6d-7a65b7679240">Dasabuvir</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Dasabuvir" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP, OATP1B1"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="2C8"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="UGT1A1, OATP1B1, OATP1B3"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|OAT: Organic Anion Transporter|OATP: Organic Anion Transporter Polypeptide|PGP: P-glycoprotein|UGT: Uridine Diphosphate Glucuronosyltransferase|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/29cedb86b8754944ae2b7fc965794aa2">Elbasvir</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP 
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>Transporters: </b>BCRP                                         
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/29cedb86b8754944ae2b7fc965794aa2">Elbasvir</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Elbasvir" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="BCRP"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="BCRP: Breast Cancer Resistance Protein|CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="">Glecaprevir</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>Transporters: </b>PGP, BCRP, OATP1B1/3                                        
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>1A2 (weak), 3A4 (weak)<br/><b>Transporters: </b>PGP, BCRP, OATP1B1/3, UGT1A1 (weak)                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs">  </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="">Glecaprevir</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Glecaprevir" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP, BCRP, OATP1B1/3"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="1A2 (weak), 3A4 (weak)"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="PGP, BCRP, OATP1B1/3, UGT1A1 (weak)"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh=""
                 data-footnotes="BCRP: Breast Cancer Resistance Protein|CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|OAT: Organic Anion Transporter|OATP: Organic Anion Transporter Polypeptide|PGP: P-glycoprotein|UGT: Uridine Diphosphate Glucuronosyltransferase">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/29cedb86b8754944ae2b7fc965794aa2">Grazoprevir</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP, OATP1B1/3 
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>3A4 (weak)<br/><b>Transporters: </b>BCRP                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/29cedb86b8754944ae2b7fc965794aa2">Grazoprevir</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Grazoprevir" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP, OATP1B1/3"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="3A4 (weak)"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="BCRP"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="BCRP: Breast Cancer Resistance Protein|CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|OAT: Organic Anion Transporter|OATP: Organic Anion Transporter Polypeptide|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/e51350dc-acf7-4aff-8f2d-3755794aa954">Ledipasvir</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>Transporters: </b>PGP, BCRP                                        
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>Transporters: </b>PGP, BCRP                                         
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/e51350dc-acf7-4aff-8f2d-3755794aa954">Ledipasvir</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Ledipasvir" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP, BCRP"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="PGP, BCRP"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="BCRP: Breast Cancer Resistance Protein|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/549f3c04-4b0c-433a-ab6d-7a65b7679240">Ombitasvir</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP 
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>Transporters: </b>2C8, UGT1A1                                         
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/549f3c04-4b0c-433a-ab6d-7a65b7679240">Ombitasvir</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Ombitasvir" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="2C8, UGT1A1"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|PGP: P-glycoprotein|UGT: Uridine Diphosphate Glucuronosyltransferase|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/549f3c04-4b0c-433a-ab6d-7a65b7679240">Paritaprevir</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>2C8, 2D6, 3A4<br/><b>Transporters: </b>PGP 
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>Transporters: </b>UGT1A1, OATP1B1                                         
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/549f3c04-4b0c-433a-ab6d-7a65b7679240">Paritaprevir</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Paritaprevir" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="2C8, 2D6, 3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="UGT1A1, OATP1B1"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|OAT: Organic Anion Transporter|OATP: Organic Anion Transporter Polypeptide|PGP: P-glycoprotein|UGT: Uridine Diphosphate Glucuronosyltransferase|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="">Pibrentasvir</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>Transporters: </b>PGP, BCRP                                        
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>1A2 (weak), 3A4 (weak)<br/><b>Transporters: </b>PGP, BCRP, OATP1B1/3, UGT1A1 (weak)                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="">Pibrentasvir</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Pibrentasvir" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP, BCRP"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="1A2 (weak), 3A4 (weak)"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="PGP, BCRP, OATP1B1/3, UGT1A1 (weak)"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="BCRP: Breast Cancer Resistance Protein|CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|OAT: Organic Anion Transporter|OATP: Organic Anion Transporter Polypeptide|PGP: P-glycoprotein|UGT: Uridine Diphosphate Glucuronosyltransferase|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/9383b8b6-25e5-4b20-9b5e-53b8c9900832">Simeprevir</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP, OATP1B1/3 
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>1A2 (weak), 3A4 (gut only)<br/><b>Transporters: </b>PGP, OATP1B1/3                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/9383b8b6-25e5-4b20-9b5e-53b8c9900832">Simeprevir</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Simeprevir" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP, OATP1B1/3"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="1A2 (weak), 3A4 (gut only)"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="PGP, OATP1B1/3"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|OAT: Organic Anion Transporter|OATP: Organic Anion Transporter Polypeptide|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/ef1070fe-3b72-4e32-ba18-dcc0c12e3411">Sofosbuvir</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>Transporters: </b>PGP, BCRP                                        
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
              &nbsp;            
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> No effect expected </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/ef1070fe-3b72-4e32-ba18-dcc0c12e3411">Sofosbuvir</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Sofosbuvir" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP, BCRP"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="No effect expected"
                 data-footnotes="BCRP: Breast Cancer Resistance Protein|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/a70e37d3759e428db5093601881c8033">Velpatasvir</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>2B6, 2C8, 3A4<br/><b>Transporters: </b>PGP, BCRP, OATP1B1/3 
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>Transporters: </b>PGP, BCRP, OATP1B1/3, OATP2B1                                         
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/a70e37d3759e428db5093601881c8033">Velpatasvir</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Velpatasvir" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="2B6, 2C8, 3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP, BCRP, OATP1B1/3"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="PGP, BCRP, OATP1B1/3, OATP2B1"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="BCRP: Breast Cancer Resistance Protein|CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|OAT: Organic Anion Transporter|OATP: Organic Anion Transporter Polypeptide|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          <tr class="drugFamily">
            <td colspan="8"><b>Antivirals (herpesvirus)</b></td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/73834cdb82a06c91981364a7c59c90a2">Cidofovir</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>Transporters: </b>OAT1, OAT3                                        
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
              &nbsp;            
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> No effect expected </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/73834cdb82a06c91981364a7c59c90a2">Cidofovir</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Cidofovir" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="OAT1, OAT3"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="No effect expected"
                 data-footnotes="OAT: Organic Anion Transporter|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/be2f151d320e45bfa907dc3a91ab7019">Letermovir</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>2D6, 3A4<br/><b>Transporters: </b>OATP1B1/3 
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>2C8, 3A4<br/><b>Transporters: </b>OATP1B1/3                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               <b>CYP450: </b>2C9, 2C19, 3A4                                           
                  
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ or ↓ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/be2f151d320e45bfa907dc3a91ab7019">Letermovir</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Letermovir" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="2D6, 3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="OATP1B1/3"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="2C8, 3A4"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="OATP1B1/3"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth="2C9, 2C19, 3A4"
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑ or ↓"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|OAT: Organic Anion Transporter|OATP: Organic Anion Transporter Polypeptide|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          <tr class="drugFamily">
            <td colspan="8"><b>Antiretrovirals</b></td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/fc1f290773d4f885b841a353849f0bb6">Atazanavir (ATV)</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP 
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>1A2, 2C8, 3A4<br/><b>Transporters: </b>UGT1A1                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/fc1f290773d4f885b841a353849f0bb6">Atazanavir (ATV)</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Atazanavir (ATV)" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="1A2, 2C8, 3A4"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="UGT1A1"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|PGP: P-glycoprotein|UGT: Uridine Diphosphate Glucuronosyltransferase|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/1c1bdbca-32d7-4a9f-b5b3-b53303299f01">Cobicistat</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>2D6, 3A4                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>2D6, 3A4<br/><b>Transporters: </b>PGP, BCRP, OATP1B1, OATP1B3                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/1c1bdbca-32d7-4a9f-b5b3-b53303299f01">Cobicistat</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Cobicistat" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="2D6, 3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="2D6, 3A4"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="PGP, BCRP, OATP1B1, OATP1B3"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="BCRP: Breast Cancer Resistance Protein|CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|OAT: Organic Anion Transporter|OATP: Organic Anion Transporter Polypeptide|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/d182a18ee8e61ff677d4e6cb678f2e2e">Darunavir (DRV)</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>3A4                                              
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/d182a18ee8e61ff677d4e6cb678f2e2e">Darunavir (DRV)</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Darunavir (DRV)" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="3A4"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/e6328cc1b11cbfc69f8a4bc9e866f2b4">Delavirdine (DLV)</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>2D6, 3A4                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>2C9, 2C19, 3A4                                              
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/e6328cc1b11cbfc69f8a4bc9e866f2b4">Delavirdine (DLV)</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Delavirdine (DLV)" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="2D6, 3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="2C9, 2C19, 3A4"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/aad6e055-f0a0-46d1-87bc-a35406003c98">Dolutegravir (DTG)</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>UGT1A1 
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
              &nbsp;            
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> No effect expected </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/aad6e055-f0a0-46d1-87bc-a35406003c98">Dolutegravir (DTG)</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Dolutegravir (DTG)" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="UGT1A1"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="No effect expected"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|UGT: Uridine Diphosphate Glucuronosyltransferase|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/98c1684e98fec65cb7cdc9d830eb8e2d">Efavirenz (EFV)</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>2B6, 3A4                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>2B6, 2C9, 2C19                                              
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               <b>CYP450: </b>2C19, 3A4                                           
                  
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ or ↓ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/98c1684e98fec65cb7cdc9d830eb8e2d">Efavirenz (EFV)</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Efavirenz (EFV)" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="2B6, 3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="2B6, 2C9, 2C19"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth="2C19, 3A4"
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑ or ↓"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/7afd5d3b-8121-4f29-845e-b20ecbf4fbc3">Elvitegravir (EVG)</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>CYP3A4<br/><b>Transporters: </b>UGT1A1/3 
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>Transporters: </b>PGP (weak)                                         
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               <b>CYP450: </b>2C9 (weak)                                           
                  
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> mild ↑ or ↓ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/7afd5d3b-8121-4f29-845e-b20ecbf4fbc3">Elvitegravir (EVG)</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Elvitegravir (EVG)" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="CYP3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="UGT1A1/3"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="PGP (weak)"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth="2C9 (weak)"
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="mild ↑ or ↓"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|PGP: P-glycoprotein|UGT: Uridine Diphosphate Glucuronosyltransferase|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/91a770f27c2c0098ea0837c21430f529">Etravirine (ETR)</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>2C9, 2C19, 3A4                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>2C9; 2C19 (weak)                                              
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               <b>CYP450: </b>3A4                                           
                  
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ or ↓ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/91a770f27c2c0098ea0837c21430f529">Etravirine (ETR)</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Etravirine (ETR)" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="2C9, 2C19, 3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="2C9; 2C19 (weak)"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth="3A4"
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑ or ↓"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/ef98f6ae40da145df1fe363d29255e07">Fosamprenavir (FPV)</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>3A4                                              
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/ef98f6ae40da145df1fe363d29255e07">Fosamprenavir (FPV)</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Fosamprenavir (FPV)" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="3A4"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/c01c90b75e2d39a28279395abccac9e2">Indinavir (IDV)</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP 
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/c01c90b75e2d39a28279395abccac9e2">Indinavir (IDV)</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Indinavir (IDV)" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="3A4"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="PGP"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/22b39301c1a91699f73a857c62c1e2cf">Lopinavir (LPV)</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
              &nbsp;            
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/22b39301c1a91699f73a857c62c1e2cf">Lopinavir (LPV)</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Lopinavir (LPV)" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/a23378a4980c0bdd672117842252d183">Maraviroc (MVC)</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP 
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>2D6                                              
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/a23378a4980c0bdd672117842252d183">Maraviroc (MVC)</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Maraviroc (MVC)" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="2D6"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/dfa124ba67dcdf49806d12489ba6dc4b">Nelfinavir (NFV)</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>2C19, 3A4<br/><b>Transporters: </b>PGP 
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               <b>CYP450: </b>3A4 (?)                                           
                  
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ or ↓ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/dfa124ba67dcdf49806d12489ba6dc4b">Nelfinavir (NFV)</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Nelfinavir (NFV)" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="2C19, 3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="3A4"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="PGP"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth="3A4 (?)"
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑ or ↓"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/82045c5bc2efdbb7ced6185fc4c57df7">Nevirapine (NVP)</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>2B6, 3A4                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
              &nbsp;            
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               <b>CYP450: </b>3A4                                           
                  
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↓ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/82045c5bc2efdbb7ced6185fc4c57df7">Nevirapine (NVP)</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Nevirapine (NVP)" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="2B6, 3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth="3A4"
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↓"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/39c5de719ecd8f880e0adeb236ca2e0d">Raltegravir (RAL)</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>Transporters: </b>UGT                                        
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
              &nbsp;            
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> No effect expected </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/39c5de719ecd8f880e0adeb236ca2e0d">Raltegravir (RAL)</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Raltegravir (RAL)" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="UGT"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="No effect expected"
                 data-footnotes="UGT: Uridine Diphosphate Glucuronosyltransferase|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/db4e32245e714aab8f439bf25669cabd">Rilpivirine (RPV)</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4                                              
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
              &nbsp;            
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> No effect expected </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/db4e32245e714aab8f439bf25669cabd">Rilpivirine (RPV)</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Rilpivirine (RPV)" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second=""
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="No effect expected"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/71216b9d6ce8def4d52c23db028571fb">Ritonavir (RTV)</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP 
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>2D6, 3A4<br/><b>Transporters: </b>PGP                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               <b>CYP450: </b>1A2, 2B6, 2C9, 2C19, 3A4 (long term)<br/><b>Transporters: </b>PGP (long term), UGT                  
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ or ↓ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/71216b9d6ce8def4d52c23db028571fb">Ritonavir (RTV)</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Ritonavir (RTV)" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="2D6, 3A4"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="PGP"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth="1A2, 2B6, 2C9, 2C19, 3A4 (long term)"
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth="PGP (long term), UGT"
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑ or ↓"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|PGP: P-glycoprotein|UGT: Uridine Diphosphate Glucuronosyltransferase|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/76452babd790152ba38bbb2c329d4104">Saquinavir (SQV)</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP 
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/76452babd790152ba38bbb2c329d4104">Saquinavir (SQV)</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Saquinavir (SQV)" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third="3A4"
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="PGP"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trOdd drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/fc1bc6f7575e4066b604d0f638c35b86">Tenofovir alaf fum (TAF)</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>Transporters: </b>PGP, BCRP, OATP1B1/3                                        
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
              &nbsp;            
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               &nbsp;     
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> No effect expected </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/fc1bc6f7575e4066b604d0f638c35b86">Tenofovir alaf fum (TAF)</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Tenofovir alaf fum (TAF)" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first=""
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP, BCRP, OATP1B1/3"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth=""
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth=""
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="No effect expected"
                 data-footnotes="BCRP: Breast Cancer Resistance Protein|CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|OAT: Organic Anion Transporter|OATP: Organic Anion Transporter Polypeptide|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
          
          <tr class="trEven drugRow">
            <td class="tblCell enz-col-1 hidden-xs"><a id="tableLink" href="/resolveuid/6cef9bff62ad7f081efd40e6edd58416">Tipranavir (TPV)</a></td>
            <td class="tblCell enz-col-2 hidden-xs">
               <b>CYP450: </b>3A4<br/><b>Transporters: </b>PGP 
                          </td>
            <td class="tblCell enz-col-3 hidden-xs">
               <b>Transporters: </b>OAT                                         
                          
            </td>
            <td class="tblCell enz-col-4 hidden-xs">
               <b>Transporters: </b>PGP (weak)                                       
                  
              
                          </td>
            <td class="tblCell enz-col-5 hidden-xs"> ↑ or ↓ </td>
            <td class="tblCell enz-col-sm-1 visible-xs"><a id="tableLink" href="/resolveuid/6cef9bff62ad7f081efd40e6edd58416">Tipranavir (TPV)</a></td>
            <td class="tblCell enz-col-sm-2 visible-xs">
              <a id="tableLink" 
                 href="#" 
                 data-toggle="modal" 
                 data-target="#rdModal" 
                 data-header="Tipranavir (TPV)" 
                 data-type="Mediated Interactions" 
                 data-firstlabel="Drug is Substrate of CYP450"
                 data-first="3A4"
                 data-secondlabel="Drug is Substrate of Transporter"
                 data-second="PGP"
                 data-thirdlabel="CYP450 Inhibited by Drug"
                 data-third=""
                 data-fourthlabel="Transporter Inhibited by Drug"
                 data-fourth="OAT"
                 data-fifthlabel="CYP450 Induced by Drug"
                 data-fifth=""
                 data-sixthlabel="Transporter Induced by Drug"
                 data-sixth="PGP (weak)"
                 data-seventhlabel="Impact on Serum Drug Concentrations"
                 data-seventh="↑ or ↓"
                 data-footnotes="CYP450 Nomenclature: e.g. 3A4: 3 = family; A = subfamily; 4 = gene|OAT: Organic Anion Transporter|OATP: Organic Anion Transporter Polypeptide|PGP: P-glycoprotein|Impact on Serum Drug Concentrations refers to serum concentrations of companion drugs that may be affected by the listed antimicrobial. ↑=increase; ↓=decrease; blank=no drugs should be affected">
                View
              </a>
            </td>
          </tr>
        
      </table>
    </div>
  </div>

<div class="modal fade" id="tooltipModal" onclick="dismissModal('#tooltipModal')">
    <div class="modal-dialog modal-sm">
      <div class="modal-content">
        <div class="modal-header">
          <h4 class="modal-title" id="tooltipModalLabel">Modal title</h4>
        </div>
        <div class="modal-body">
          <h3>Modal Body</h3>
        </div>
        <div class="modal-footer">
            <button type="button" class="btn btn-default" data-dismiss="modal">Close</button>
        </div>
      </div>
    </div>
  </div>
  
  <div class="modal fade" id="searchModal">
    <div class="modal-dialog modal-sm">
      <div class="modal-content">
        <div class="modal-body modal-grad">
          <input type="text" class="searchBox searchSm" id="search2" placeholder="Search Mediated Interactions" style="vertical-align: middle;"/>
          <br/>
          <button type="button" class="btn btn-default" data-dismiss="modal">Search</button>
          <button type="button" class="btn btn-default" data-dismiss="modal" onclick="clearSearch()">Cancel</button>
        </div>
      </div>
    </div>
  </div>


<div class="modal fade" id="rdModal" onclick="dismissModal('#rdModal')">
    <div class="modal-dialog modal-sm" tabindex="-1" role="dialog">
        <div class="modal-content">
            <div class="modal-header">
                <h4 class="modal-title" id="tooltipModalLabel">Modal title</h4>
            </div>
            <div class="modal-body">
                <h3>Modal Body</h3>
            </div>
            <div class="modal-footer">
                <button type="button" class="btn btn-default" data-dismiss="modal">Close</button>
            </div>
        </div>
    </div>
</div>

  <script type="text/javascript" src="scripts/tablesearch2.js"></script>
  <script type="text/javascript" src="scripts/dosingtables2.js"></script>
  

</body>
</html>